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Mary O'Leary

Postdoctoral Research Associate

 4759

 Haighton 

 

University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK

Overview

Mary is a postdoctoral researcher working with Prof Jo Bowtell. She is currently working on research projects investigating the effects of bioactive compounds on exercise-induced muscle damage, and postmenopausal bone and muscle health. She has recieved Co-Investigator funding from the Cherry Marketing Institute, Pukka Herbs and an ESRC IAA Rapid Response Fund award.

Mary completed a Wellcome Trust supported MRes/PhD programme at the University of Birmingham in 2018. Her PhD work investigated the role of adipose and skeletal muscle derived cytokines in in vitro human myogenesis and was supervised by was co-supervised by Dr Simon Jones, Dr Graham Wallace and Dr Kostas Tsintzas.

Her research interests include the functions of skeletal muscle myogenesis in adult human muscle and the effects of adiposity and inflammation in the ageing musculoskeletal system.

Prior to completing her PhD, Mary completed a Medical Degree at University College Cork and Master's Degrees at the Universities of Nottingham and Birmingham.

Qualifications

2011 - MB, BCh, BAO, University College Cork.

2013 - MSc Integrated Physiology, University of Nottingham.

2014 - MRes Biomedical Research, University of Birmingham.

2018 - PhD, Institute of Inflammation and Ageing, University of Birmingham.

  • 'The role of adipose and skeletal muscle derived cytokines in human myogenesis: implications for ageing skeletal muscle.'

Research

Publications

Key publications | Publications by category | Publications by year

Publications by category


Journal articles

O'Leary M, Barreto M, Bowtell J (2019). Evaluating the effect of a home-delivered meal service on the physical and psychological wellbeing of a UK population of older adults—A pilot and feasibility study. Journal of Nutrition in Gerontology and Geriatrics Full text.
Murphy D, Nicholson T, Jones S, O'Leary M (2019). MyoCount: a software tool for the automated quantification of myotube surface area and nuclear fusion index. Wellcome Open Research Full text.
Lear R, O'Leary M, O'Brien Andersen L, Holt CC, Stensvold CR, van der Giezen M, Bowtell JL (2019). Tart Cherry Concentrate Does Not Alter the Gut Microbiome, Glycaemic Control or Systemic Inflammation in a Middle-Aged Population. Nutrients, 11(5). Abstract.  Author URL.  Full text.
O'Leary MF, Wallace GR, Davis ET, Murphy DP, Nicholson T, Bennett AJ, Tsintzas K, Jones SW (2018). Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB. Scientific Reports Full text.
O’Leary MF, Wallace GR, Bennett AJ, Tsintzas K, Jones SW (2017). IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development. Scientific Reports, 7(1). Full text.
Song Z, Moore DR, Hodson N, Ward C, Dent JR, O’Leary MF, Shaw AM, Hamilton DL, Sarkar S, Gangloff Y-G, et al (2017). Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle. Scientific Reports, 7(1). Full text.
Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, et al (2016). 11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. The Journal of Pathology, 240(4), 472-483. Full text.
Kavanagh D, Boulton A, O'leary M, Suresh S, Newsome PN, Kalia N (2014). P351Pretreatment of mesenchymal stem cells does not enhance their recruitment to injured tissue in a model of ischemia-reperfusion injury yet abolishes their anti-inflammatory capabilities. Cardiovascular Research, 103(suppl 1), S64.2-S64.

Conferences

Philp A, Pearson M, O'Leary M, Jones S (2018). ASSOCIATION OF CHEMERIN LEVELS IN SERUM AND SYNOVIAL FLUID WITH THE SEVERITY OF HIP OSTEOARTHRITIS.  Author URL.

Publications by year


2019

O'Leary M, Barreto M, Bowtell J (2019). Evaluating the effect of a home-delivered meal service on the physical and psychological wellbeing of a UK population of older adults—A pilot and feasibility study. Journal of Nutrition in Gerontology and Geriatrics Full text.
Murphy D, Nicholson T, Jones S, O'Leary M (2019). MyoCount: a software tool for the automated quantification of myotube surface area and nuclear fusion index. Wellcome Open Research Full text.
Lear R, O'Leary M, O'Brien Andersen L, Holt CC, Stensvold CR, van der Giezen M, Bowtell JL (2019). Tart Cherry Concentrate Does Not Alter the Gut Microbiome, Glycaemic Control or Systemic Inflammation in a Middle-Aged Population. Nutrients, 11(5). Abstract.  Author URL.  Full text.

2018

Philp A, Pearson M, O'Leary M, Jones S (2018). ASSOCIATION OF CHEMERIN LEVELS IN SERUM AND SYNOVIAL FLUID WITH THE SEVERITY OF HIP OSTEOARTHRITIS.  Author URL.
O'Leary MF, Wallace GR, Davis ET, Murphy DP, Nicholson T, Bennett AJ, Tsintzas K, Jones SW (2018). Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB. Scientific Reports Full text.

2017

O’Leary MF, Wallace GR, Bennett AJ, Tsintzas K, Jones SW (2017). IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development. Scientific Reports, 7(1). Full text.
Song Z, Moore DR, Hodson N, Ward C, Dent JR, O’Leary MF, Shaw AM, Hamilton DL, Sarkar S, Gangloff Y-G, et al (2017). Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle. Scientific Reports, 7(1). Full text.

2016

Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, et al (2016). 11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. The Journal of Pathology, 240(4), 472-483. Full text.

2014

Kavanagh D, Boulton A, O'leary M, Suresh S, Newsome PN, Kalia N (2014). P351Pretreatment of mesenchymal stem cells does not enhance their recruitment to injured tissue in a model of ischemia-reperfusion injury yet abolishes their anti-inflammatory capabilities. Cardiovascular Research, 103(suppl 1), S64.2-S64.

Mary_OLeary Details from cache as at 2019-11-22 04:33:06

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