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Dr Mary O'Leary

Senior Research Fellow

 4759

 Haighton 

 

University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK

Overview

Mary is a Senior Research Fellow working within the BioActivEx research group. She is currently working on research projects investigating the effects of bioactive compounds on exercise-induced muscle damage, and postmenopausal bone and muscle health. She has recieved Principal Investigator funding from Pukka Herbs and pre-seedcorn funding from the Wellcome Trust-supported Translational Research Exchange at Exeter. She has received a Co-Investigator funding via PepsiCo, the Cherry Marketing Institute and an ESRC IAA Rapid Response Fund award. She is the primary supervisor to one PhD student and co-supervises two PhD students with Prof Jo Bowtell.

Mary is an Associate Fellow of the Higher Education Academy and has completed an Advanced Certificate in Learning and Teaching in Higher Education. She is a Scientific Communication Tutor for the BSc in Medical Sciences and contributes to laboratory practical teaching for the BSc in Exercise and Sport Sciences. She has previously been a Respiratory Medicine Tutor at the University of Birmingham and has taught on the University of Birmingham's MSc in Musculoskeletal Ageing.

Mary completed a Wellcome Trust supported MRes/PhD programme at the University of Birmingham in 2018. Her PhD work investigated the role of adipose and skeletal muscle derived cytokines in in vitro human myogenesis and was supervised by Dr Simon Jones and co-supervised by Dr Graham Wallace and Dr Kostas Tsintzas.

Her research interests include the functions of skeletal muscle myogenesis in adult human muscle and the effects of adiposity and inflammation in the ageing musculoskeletal system. 

Prior to completing her PhD, Mary completed a Medical Degree (MB BCh BAO) at University College Cork and Master's Degrees at the Universities of Nottingham and Birmingham.

Qualifications

2011 - MB, BCh, BAO, University College Cork.

2013 - MSc Integrated Physiology, University of Nottingham.

2014 - MRes Biomedical Research, University of Birmingham.

2018 - PhD, Institute of Inflammation and Ageing, University of Birmingham.

  • 'The role of adipose and skeletal muscle derived cytokines in human myogenesis: implications for ageing skeletal muscle.'

Research

Publications

Key publications | Publications by category | Publications by year

Key publications


Wangdi JT, O'Leary MF, Kelly VG, Jackman SR, Tang JCY, Dutton J, Bowtell JL (2021). Tart Cherry Supplement Enhances Skeletal Muscle Glutathione Peroxidase Expression and Functional Recovery after Muscle Damage. Med Sci Sports Exerc Abstract.  Author URL.

Publications by category


Journal articles

Sabou VR, O'Leary MF, Liu Y, Brown PN, Murch S, Bowtell JL (2021). Review of Analytical Methods and Reporting of the Polyphenol Content of Tart Cherry Supplements in Human Supplementation Studies Investigating Health and Exercise Performance Effects: Recommendations for Good Practice. Frontiers in Nutrition, 8 Abstract.
Wangdi JT, O'Leary MF, Kelly VG, Jackman SR, Tang JCY, Dutton J, Bowtell JL (2021). Tart Cherry Supplement Enhances Skeletal Muscle Glutathione Peroxidase Expression and Functional Recovery after Muscle Damage. Med Sci Sports Exerc Abstract.  Author URL.
Wangdi JT, Sabou V, O'Leary MF, Kelly VG, Bowtell JL (2021). Use, Practices and Attitudes of Elite and Sub-Elite Athletes towards Tart Cherry Supplementation. Sports (Basel), 9(4). Abstract.  Author URL.
Hodson N, Dent JR, O'Leary MF, Song Z, Nicholson T, Jones SW, Murray JT, Jeromson S, Hamilton DL, Breen L, et al (2020). Protein‐carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle. Experimental Physiology
Sabou V, Wangdi J, O’Leary MF, Kelly VG, Bowtell JL (2020). Use, Practices and Attitudes of Sports Nutrition and Strength and Conditioning Practitioners towards Tart Cherry Supplementation. Sports, 9(1), 2-2. Abstract.
O'Leary M, Barreto M, Bowtell J (2019). Evaluating the effect of a home-delivered meal service on the physical and psychological wellbeing of a UK population of older adults—A pilot and feasibility study. Journal of Nutrition in Gerontology and Geriatrics
Murphy D, Nicholson T, Jones S, O'Leary M (2019). MyoCount: a software tool for the automated quantification of myotube surface area and nuclear fusion index. Wellcome Open Research
Lear R, O'Leary M, O'Brien Andersen L, Holt CC, Stensvold CR, van der Giezen M, Bowtell JL (2019). Tart Cherry Concentrate Does Not Alter the Gut Microbiome, Glycaemic Control or Systemic Inflammation in a Middle-Aged Population. Nutrients, 11(5). Abstract.  Author URL.
O'Leary MF, Wallace GR, Davis ET, Murphy DP, Nicholson T, Bennett AJ, Tsintzas K, Jones SW (2018). Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB. Scientific Reports
O’Leary MF, Wallace GR, Bennett AJ, Tsintzas K, Jones SW (2017). IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development. Scientific Reports, 7(1).
Song Z, Moore DR, Hodson N, Ward C, Dent JR, O’Leary MF, Shaw AM, Hamilton DL, Sarkar S, Gangloff Y-G, et al (2017). Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle. Scientific Reports, 7(1).
Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, et al (2016). 11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. The Journal of Pathology, 240(4), 472-483.
Kavanagh D, Boulton A, O'leary M, Suresh S, Newsome PN, Kalia N (2014). P351Pretreatment of mesenchymal stem cells does not enhance their recruitment to injured tissue in a model of ischemia-reperfusion injury yet abolishes their anti-inflammatory capabilities. Cardiovascular Research, 103(suppl 1), S64.2-S64.

Conferences

Philp A, Pearson M, O'Leary M, Jones S (2018). ASSOCIATION OF CHEMERIN LEVELS IN SERUM AND SYNOVIAL FLUID WITH THE SEVERITY OF HIP OSTEOARTHRITIS.  Author URL.

Publications by year


2021

Sabou VR, O'Leary MF, Liu Y, Brown PN, Murch S, Bowtell JL (2021). Review of Analytical Methods and Reporting of the Polyphenol Content of Tart Cherry Supplements in Human Supplementation Studies Investigating Health and Exercise Performance Effects: Recommendations for Good Practice. Frontiers in Nutrition, 8 Abstract.
Wangdi JT, O'Leary MF, Kelly VG, Jackman SR, Tang JCY, Dutton J, Bowtell JL (2021). Tart Cherry Supplement Enhances Skeletal Muscle Glutathione Peroxidase Expression and Functional Recovery after Muscle Damage. Med Sci Sports Exerc Abstract.  Author URL.
Wangdi JT, Sabou V, O'Leary MF, Kelly VG, Bowtell JL (2021). Use, Practices and Attitudes of Elite and Sub-Elite Athletes towards Tart Cherry Supplementation. Sports (Basel), 9(4). Abstract.  Author URL.

2020

Hodson N, Dent JR, O'Leary MF, Song Z, Nicholson T, Jones SW, Murray JT, Jeromson S, Hamilton DL, Breen L, et al (2020). Protein‐carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle. Experimental Physiology
Sabou V, Wangdi J, O’Leary MF, Kelly VG, Bowtell JL (2020). Use, Practices and Attitudes of Sports Nutrition and Strength and Conditioning Practitioners towards Tart Cherry Supplementation. Sports, 9(1), 2-2. Abstract.

2019

O'Leary M, Barreto M, Bowtell J (2019). Evaluating the effect of a home-delivered meal service on the physical and psychological wellbeing of a UK population of older adults—A pilot and feasibility study. Journal of Nutrition in Gerontology and Geriatrics
Murphy D, Nicholson T, Jones S, O'Leary M (2019). MyoCount: a software tool for the automated quantification of myotube surface area and nuclear fusion index. Wellcome Open Research
Lear R, O'Leary M, O'Brien Andersen L, Holt CC, Stensvold CR, van der Giezen M, Bowtell JL (2019). Tart Cherry Concentrate Does Not Alter the Gut Microbiome, Glycaemic Control or Systemic Inflammation in a Middle-Aged Population. Nutrients, 11(5). Abstract.  Author URL.

2018

Philp A, Pearson M, O'Leary M, Jones S (2018). ASSOCIATION OF CHEMERIN LEVELS IN SERUM AND SYNOVIAL FLUID WITH THE SEVERITY OF HIP OSTEOARTHRITIS.  Author URL.
O'Leary MF, Wallace GR, Davis ET, Murphy DP, Nicholson T, Bennett AJ, Tsintzas K, Jones SW (2018). Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB. Scientific Reports

2017

O’Leary MF, Wallace GR, Bennett AJ, Tsintzas K, Jones SW (2017). IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development. Scientific Reports, 7(1).
Song Z, Moore DR, Hodson N, Ward C, Dent JR, O’Leary MF, Shaw AM, Hamilton DL, Sarkar S, Gangloff Y-G, et al (2017). Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle. Scientific Reports, 7(1).

2016

Hardy RS, Doig CL, Hussain Z, O'Leary M, Morgan SA, Pearson MJ, Naylor A, Jones SW, Filer A, Stewart PM, et al (2016). 11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. The Journal of Pathology, 240(4), 472-483.

2014

Kavanagh D, Boulton A, O'leary M, Suresh S, Newsome PN, Kalia N (2014). P351Pretreatment of mesenchymal stem cells does not enhance their recruitment to injured tissue in a model of ischemia-reperfusion injury yet abolishes their anti-inflammatory capabilities. Cardiovascular Research, 103(suppl 1), S64.2-S64.

Mary_OLeary Details from cache as at 2021-11-28 12:50:17

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Teaching

Supervision / Group

Postgraduate researchers

  • Celeste Lugtmeijer
  • Vlad Razvan Sabou
  • Jimmy Wangdi

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